Amal El Hamsas El Youbi | Author | IgMin Research - A Multidisciplinary Open Access Journal

Biography

Dr. Amal El Hamsas El Youbi is a distinguished professor at the University Hassan II of Casablanca, Morocco, where she leads the Laboratory of Biology and Health within the Department of Biology at the Faculty of Sciences Ben M’Sik. Her academic journey is marked by a commitment to advancing research in pharmacology, immunology, and the bioactivity of natural compounds.

Dr. El Youbi's research primarily focuses on the medicinal properties of plants and natural products. She has co-authored several significant studies, including investigations into the antioxidant, anti-inflammatory, and antidiabetic properties of polyphenols from coriander seeds . Another notable work examines the pharmacological effects of bioactive extracts from the rhizome of Aristolochia longa, highlighting its immunomodulatory and cytotoxic activities.

In 2023, Dr. El Youbi contributed to a pivotal study published in IgMin Research, exploring the antidepressant and antioxidant properties of dietary proteins derived from egg and bean extracts. This research revealed the previously unexplored pharmacognostic potential of antidepressants found in nutrients derived from both legume and animal sources.

Her scholarly impact is recognized globally, with an H-index of 13 and over 370 citations, positioning her among the top researchers in biological sciences both in Morocco and internationally .

Dr. El Youbi's work continues to inspire advancements in the field of pharmacognosy, bridging traditional knowledge with modern scientific inquiry.

Research Interest

Dr. Amal El Hamsas El Youbi’s research interests lie in the field of pharmacognosy, focusing on the bioactivity of natural compounds and their therapeutic potential. She is particularly interested in the medicinal properties of plants and natural products, exploring their antioxidant, anti-inflammatory, and antidiabetic effects. Her work examines the bioactive compounds found in various plant species, aiming to identify novel natural remedies with pharmacological applications. Dr. El Youbi’s research also extends to the study of immunomodulatory and cytotoxic activities of plant extracts, investigating their potential in treating diseases such as cancer and diabetes. Additionally, her work on dietary proteins and their antidepressant properties contributes to the growing body of research on nutrition and mental health. Through her studies, Dr. El Youbi seeks to bridge traditional knowledge with modern science, advancing the understanding of natural products as a source of therapeutics for various health conditions.

Medicine Group (1)

Research Article Article ID: igmin114

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The Antioxidant and Antidepressant Properties of Dietary Proteins Derived from Egg and Bean Extracts and Their Acute Toxicity: A Journey from Nutrition to Pharmacognosy

by Amal El Hamsas El Youbi, Omaima Boudaia, Zineb Sekkout, Najat El Amrani and Driss Radallah

This research reveals the previously unexplored pharmacognostic potential of antidepressants found in nutrients derived from both legume and animal sources. Through preclinical investigations involving mouse models, the study focused into antidepressant and antioxidant activities of non-denatured and denatured protein extracts from beans and eggs. Non-denatured protein extracts from beans and eggs, at saturation levels of 40% and 80%, were examined as macronutrients, while denatured protein extracts at equivalent saturation levels were consider...ed micronutrients. The study employed the DPPH and hydrogen peroxide tests to assess antioxidant activity, and the forced swimming test and sucrose preference test to evaluate acute and chronic mild antidepressant effects, respectively. The acute toxicity study revealed that macronutrients from eggs at 40% and 80% saturation displayed non-toxic effects (LD50 >5 g/kg), while those from beans, specifically at saturation of 80%, exhibited a relatively low level of toxicity (LD50 = 2.5 g/kg). Evaluation of antioxidant activity using the DPPH test yielded inconclusive results due to the influence of ethanol precipitation. In contrast, the H2O2 test demonstrated significant antioxidant potential in both macronutrients and micronutrients extracted from beans and eggs at all saturation levels. In investigating antidepressant properties, both macronutrients and micronutrients of bean and egg protein extracts at 40% and 80% saturation exhibited notable antidepressant effects, particularly the micronutrients at saturation of 80%. This antidepressant effect was characterized by a reduction in immobility time and an increase in sucrose preference.In conclusion, this study uncovers the multifaceted potential of protein extracts sourced from natural products, plant and animal origins, as agents for treating depression. It opens up new avenues for research, with implications ranging from neuroprotection to the management of depression, inspiring optimism for innovative approaches to mental health treatment.