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Abstract

Olga Golovanova 著者 at IgMin Research

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Biography

Dr. Olga A. Golovanova leads the Department of Inorganic Chemistry at F.M. Dostoevsky Omsk State University, located at Mira St. 55a, Omsk, Russia. Her ORCID (0000‑0003‑4995‑7789) confirms her identity and affiliation. With over 40 published works and more than 140 citations, she is a recognized expert in the fields of coordination chemistry, biomineralization, and materials science.

A significant portion of her research focuses on synthesizing and characterizing calcium phosphate materials—such as hydroxyapatite, brushite, and carbonate hydroxyapatite—and their modifications with rare earth elements (La, Ce) or polymers like chitosan and alginate. In 2025 alone, Dr. Golovanova contributed to a groundbreaking study on hydroxyapatite substituted with lanthanum and cerium, demonstrating reduced solubility and potential in bone tissue engineering 

Notably, her article titled “Biomimetic Synthesis of Calcium Carbonate in Bile in the Presence of Amino Acids” investigates how bile components and amino acids influence mineral formation and dissolution processes—key to understanding gallstone disease Earlier work includes spectrophotometric studies on magnesium and calcium amino acid complexes, contributing to knowledge of biomineral formation in physiological fluids.

Beyond materials chemistry, Dr. Golovanova has advanced theoretical models for calcium phosphate crystallization under simulated biological conditions, addressing processes relevant to bone health and pathology.

Her leadership in both experimental and theoretical inorganic chemistry, combined with interdisciplinary collaborations, underscores her significant impact in biochemistry, medical chemistry, and materials science—solidifying her status as a leading figure at Omsk State University and in global scientific communities.

Research Interest

Dr. Olga A. Golovanova’s research is centered on the synthesis, characterization, and modification of calcium phosphate-based biomaterials, particularly hydroxyapatite, brushite, and carbonate hydroxyapatite. Her work explores the incorporation of rare earth elements (e.g., lanthanum, cerium) and natural polymers (such as chitosan and alginate) to enhance the physicochemical and biological properties of these materials for biomedical applications. She is deeply involved in studying biomineralization processes and the formation of pathogenic minerals, including gallstones and kidney stones, under physiological and simulated conditions. Her research extends to complexation reactions between amino acids and essential metals like calcium and magnesium, aiming to understand biochemical pathways of mineral formation and dissolution. Additionally, she investigates the solubility, crystallinity, and bioactivity of modified apatites for applications in bone regeneration, drug delivery, and tissue engineering. Dr. Golovanova’s interdisciplinary approach bridges inorganic chemistry, medical science, and materials engineering to develop innovative solutions for healthcare and biotechnology.

General Science Group (1)

Research Article Article ID: igmin227
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Biomimetic Synthesis of Calcium Carbonate in Bile in the presence of Amino Acids
by Olga Golovanova

Thermodynamic and experimental modeling of calcium carbonate crystallization in a model solution of human bile has been carried out. The process of calcium carbonate (calcite and vaterite) crystallization from solutions containing bile has been studied. It is shown that differences in the phase and group composition of the samples arise depending on the synthesis parameters. It has been established that in the presence of 1 wt. % bile, calcite is formed, and an increase in the concentration of bile in the initial solution from 5 to 100 wt. % co...ntributes to the crystallization of vaterite. It is shown that the mass of the solid phase increases with an increase in the concentration of bile in the initial solution. The dissolution of the synthesized samples was performed in 0.9 wt. % NaCl solution and 0.05 M EDTA solution. It was found that the presence of bile components in the composition of solid samples reduces the rate of their dissolutions.

Chemistry Biochemistry
Olga Golovanova

Author

仕事内容

 Omsk State University

 Department of Inorganic Chemistry, The Department of Сhemistry, Omsk State University is Named after F.M. Dostoevsky, Mira St., 55a. Omsk, 644077, Russia

 Russia

ORCID 0000-0003-4995-7789

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